Everything about Intramuscular Fat totally explained
Intramuscular fat or
Intramuscular triglycerides (IMTG) is located throughout
skeletal muscle and is responsible for the
marbling seen in certain cuts of
beef. In humans, excess accumulation of intramuscular fat is associated with
insulin resistance and
type 2 diabetes. The human immunodeficiency virus (HIV)-
lipodystrophy syndrome is associated with over-accumulation of intramuscular fat which may contribute to
AIDS wasting syndrome.
Diabetes
IMTG is known to be a cause of
type 2 diabetes though this is only true for those individuals with a high level of
adipose tissue as well. Athletes also have a high level of IMTG which is favorable for energy uptake via
mitochondria.
Insulin Resistance
Increased supply of
adipose tissue correlates with the increased accumulation of IMTG which both can lead to
insulin resistance in the muscles. Athletes often don't exhibit this correlation as they're typically insulin sensitive while having high levels of IMTG. It is thought that the improved efficiency of trained
skeletal muscles prevents the development of insulin resistance.
Exercise
"Intramuscular triacylglycerol (IMTG) represents an energy store that can be used during exercise, when it may contribute up to 20% of total energy turnover depending on diet, gender, and exercise type."
It is thought that a low calorie diet and exercise induced proteins (
Sterol regulatory element-binding proteins) are what cause high levels of IMTG in the skeletal muscle of trained athletes. This is in contrast to the build-up of IMTG in the obese which correlates to high levels of adipose tissue.
Women have been shown to use more IMTG during exercise than men which directly correlates to the higher IMTG content in women over men.
Further Information
Get more info on 'Intramuscular Fat'.
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